How many aspirin can you take in a day?

Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that is used over the counter (OTC) for the temporary relief of mild to moderate aches and pains, fever and swelling.

The U.S. Food and Drug Administration (FDA) recommends adults take no more than 4,000 milligrams (mg) of aspirin in a 24-hour period. Doses of OTC aspirin should not exceed more than 650 mg every four hours, or 975 mg every six hours.

Take aspirin exactly as directed on the package label or as prescribed by your healthcare provider. Do not use aspirin in larger doses or for longer than recommended. Aspirin may be used under medical supervision in the treatment and prevention of other medical conditions, such as rheumatoid arthritis and heart conditions, as well as stroke and cancer prevention. If you are taking aspirin under medical supervision, follow your healthcare provider’s instructions.

Aspirin is not appropriate for everyone, so be sure to talk to your healthcare provider before taking aspirin. OTC aspirin should not be used in children under the age of 12 without consulting a healthcare provider first. Never give aspirin to anyone under the age of 18 who has, or is recovering from, a viral illness such as flu or chickenpox. The use of aspirin in these individuals can cause a rare but life-threatening condition called Reye’s syndrome.

If you suspect that you or someone you know may have taken too much aspirin or have aspirin poisoning, contact your local poison control center or seek emergency care.

Published June 2022.